Video: Guardian of the genome


The tumour-suppressing protein referred to as p53, also called the guardian of the genome, protects our cells from mobile injury. Underneath mobile stress, p53 jumps into motion, regulating gene expression to manage DNA restore, cell division and cell dying.

However, p53 malfunction is related to an unlimited array of adverse to deal with cancers, and these can come up both from mutations within the TP53 gene, or by an overabundance of a regulatory protein that retains p53 inactive. Sadly, there are not any catch-all medicine to sort out all these most cancers, however a number of mixture therapies are present process analysis, providing hope for the longer term.

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